Adenosin | 58-61-7

Adenosine, wani nucleoside wanda ya ƙunshi adenine da ribose, yana da mahimman aikace-aikace masu mahimmanci a cikin magani da ilimin lissafin jiki saboda tasirin ilimin lissafi akan tsarin daban-daban a cikin jiki.

Magungunan cututtukan zuciya:

Kayan aikin Ganewa: Ana amfani da Adenosine azaman wakili na damuwa na harhada magunguna yayin gwaje-gwajen damuwa na zuciya, kamar hoton bugun zuciya na zuciya. Yana taimakawa wajen tantance cututtukan jijiyoyin jini ta hanyar haifar da vasodilation na jijiyoyin jini, yana kwaikwayon tasirin motsa jiki na jiki.

Jiyya na Supraventricular Tachycardia (SVT): Adenosine magani ne na farko don kawo karshen sassan SVT. Yana aiki ta hanyar jinkirin gudanarwa ta kumburin atrioventricular, yana katse hanyoyin sake shigowa da ke da alhakin SVT.

Neurology:

Sarrafa Kamewa: Adenosine wani maganin hana daukar ciki ne a cikin kwakwalwa. Modulating adenosine receptors iya samun antiepileptic effects, kuma adenosine-sakewa jamiái ana bincike a matsayin m jiyya ga farfadiya.

Neuroprotection: Masu karɓa na Adenosine suna taka rawa wajen kare ƙwayoyin cuta daga raunin ischemic da damuwa na oxidative. Bincike ya bincika yuwuwar adenosine a matsayin wakili na neuroprotective a cikin bugun jini da cututtukan neurodegenerative kamar Parkinson's da Alzheimer's.

Maganin Numfashi:

Bronchodilator: Adenosine yana aiki a matsayin bronchodilator kuma ana amfani dashi a gwajin bronchoprovocation don gano cutar asma. Yana haifar da ɓarna a cikin mutanen da ke da asma, yana taimakawa wajen gano hyperreactivity na iska.

Abubuwan Antiarrhythmic:

Adenosine na iya kashe wasu nau'ikan arrhythmias ta hanyar daidaita ayyukan lantarki a cikin zuciya, musamman a cikin kumburin atria da kumburin atrioventricular. Shortarancin rabin rayuwar sa yana iyakance tasirin tsarin.

Kayan Aikin Bincike:

Adenosine da analogs ana amfani da su sosai a cikin bincike don nazarin rawar adenosine receptors a cikin nau'ikan hanyoyin ilimin lissafi da ilimin cututtuka. Suna taimakawa bayyana ayyukan adenosine a cikin neurotransmission, amsawar rigakafi, kumburi, da tsarin tsarin zuciya.

Aikace-aikace masu yuwuwar warkewa:

Ana bincikar magunguna na tushen Adenosine don yuwuwar aikace-aikacen warkewa a cikin yanayi kamar ciwon daji, rauni na ischemic, kula da ciwo, da cututtukan kumburi. Adenosine receptor agonists da antagonists suna daga cikin mahadi da ake nazarin.