Huperzine A ｜120786-18-7

Huperzine A shine haɓakar fahimi wanda ke hana enzymes waɗanda ke lalata ilimin neurotransmitter acetylcholine. Yana cikin nau'in cholinergic na kwayoyin halitta waɗanda zasu iya taimakawa wajen magance raguwar fahimi a cikin tsofaffi.

Huperzine A wani fili ne da aka samo daga dangin huperzine. Ana kiransa mai hana acetylcholinesterase, wanda ke nufin yana hana enzyme daga rushe acetylcholine, yana haifar da karuwa a cikin acetylcholine.

Acetylcholine ana kiransa mai ilmantarwa neurotransmitter kuma yana da hannu cikin raunin tsoka.

Huperzine A ya bayyana azaman fili mai aminci. Guba da kuma nazarin ɗan adam daga nazarin dabbobi ba su nuna wani sakamako mai illa ba a ƙarin allurai na al'ada. Hakanan ana amfani da Huperzine A a cikin gwaji na farko don hana cutar Alzheimer.

Huperzine A yana faruwa a cikin ruwan cerebrospinal kuma cikin sauƙi ya ketare shingen jini-kwakwalwa.

Huperzine A shine mafi sani da mai hana acetylcholinesterase. Musamman, yana hana nau'in G4 na acetylcholinesterase, wanda ya zama ruwan dare a cikin kwakwalwar dabbobi masu shayarwa. Ya fi tasiri ko daidai daidai da sauran masu hana acetylcholinesterase, kamar tacillin ko rivastatin. A matsayin mai hanawa, yana da babban alaƙa ga acetylcholinesterase. A lokaci guda kuma, tana da saurin rabuwa da juna, wanda ke sa rabin rayuwarta ta yi tsayi sosai.

Baya ga hana acetylcholinesterase, ana iya ganin shi azaman neuroprotective akan glutamate, beta amyloid pigmentation, da guba mai haifar da H2O2.

Huperzine A na iya haɓaka haɓakar ƙwayoyin ƙwayoyin cuta na hippocampal (NSCs). Da alama yana haɓaka haɓakar jijiyoyi a allurai masu alaƙa.