Adenosine 5'-monophosphate | 61-19-8

Adenosine 5'-monophosphate (AMP) wani nucleotide ne wanda ya ƙunshi adenine, ribose, da rukunin phosphate guda ɗaya.

Tsarin Sinadarai: An samo AMP daga adenosine nucleoside, inda adenine ke da alaƙa da ribose, kuma an haɗa ƙarin rukunin phosphate zuwa 5' carbon na ribose ta hanyar haɗin phosphoester.

Matsayin Halittu: AMP muhimmin sashi ne na acid nucleic, yana aiki azaman monomer a cikin ginin ƙwayoyin RNA. A cikin RNA, an shigar da AMP cikin sarkar polymer ta hanyar haɗin phosphodiester, yana kafa kashin bayan madaidaicin RNA.

Metabolism na Makamashi: AMP kuma yana da hannu a cikin metabolism na makamashin salula. Yana aiki a matsayin precursor zuwa adenosine diphosphate (ADP) da adenosine triphosphate (ATP) ta hanyar phosphorylation halayen catalyzed ta enzymes kamar adenylate kinase. ATP, musamman, shine mai ɗaukar makamashi na farko a cikin sel, yana ba da kuzari ga hanyoyin tafiyar matakai daban-daban.

Tsarin Metabolic: AMP yana taka rawa wajen daidaita ma'aunin makamashin salula. Matakan AMP na salula na iya canzawa don amsawa ga canje-canjen rayuwa da buƙatun kuzari. Matsakaicin matakan AMP dangane da ATP na iya kunna hanyoyin gano makamashin salula, irin su AMP-activated protein kinase (AMPK), wanda ke daidaita metabolism don kula da homeostasis makamashi.

Tushen Abincin: Ana iya samun AMP daga tushen abinci, musamman a cikin abinci masu wadatar sinadarai na nucleic, kamar nama, kifi, da legumes.

Aikace-aikacen Magunguna: An bincika AMP da abubuwan da suka samo asali don yuwuwar aikace-aikacen warkewa. Misali, cAMP (AMP na cyclic), wanda ya samo asali daga AMP, yana aiki a matsayin manzo na biyu a cikin hanyoyin watsa sigina kuma ana yin niyya ta hanyar magunguna daban-daban don kula da yanayi kamar asma, cututtukan zuciya, da rashin daidaituwa na hormonal.