Uridine |58-96-8

Uridine shine pyrimidine nucleoside wanda ke aiki a matsayin tushen tushen ginin RNA (ribonucleic acid), ɗaya daga cikin manyan nau'ikan acid nucleic guda biyu masu mahimmanci don adanawa da watsa bayanan kwayoyin halitta a cikin sel.

Tsarin Sinadarai: Uridine ya ƙunshi tushen uracil na pyrimidine da ke haɗe zuwa ribose ɗin sukari mai carbon biyar ta hanyar haɗin β-N1-glycosidic.

Matsayin Halittu:

Toshe Ginin RNA: Uridine wani muhimmin sashi ne na RNA, inda ya zama kashin bayan kwayoyin RNA tare da sauran nucleosides kamar adenosine, guanosine, da cytidine.

Messenger RNA (mRNA): A cikin mRNA, ragowar uridine suna ɓoye bayanan kwayoyin halitta yayin rubutawa, ɗauke da umarni daga DNA zuwa injin haɗin furotin a cikin tantanin halitta.

Canja wurin RNA (tRNA): Uridine kuma yana cikin ƙwayoyin intRNA, inda yake shiga cikin tsarin fassarar ta hanyar gane takamaiman codons da isar da amino acid daidai ga ribosome.

Metabolism: Ana iya haɗa Uridine de novo a cikin sel ko samu daga tushen abinci.Ana samar da shi ta hanyar juyawar enzymatic na orotidine monophosphate (OMP) ko uridine monophosphate (UMP) a cikin hanyar biosynthesis na pyrimidine.

Muhimmancin Jiki:

Neurotransmitter Precursor: Uridine yana taka rawa a aikin kwakwalwa da haɓakawa.Yana da precursor don kira na phospholipids na kwakwalwa, ciki har da phosphatidylcholine, wanda ke da mahimmanci don amincin membrane na neuronal da siginar neurotransmitter.

Sakamakon Neuroprotective: An yi nazarin Uridine don yuwuwar abubuwan da ke haifar da ƙwayoyin cuta da ikon haɓaka aikin synaptic da filastik neuronal.

Yiwuwar warkewa:

An bincika Uridine da abubuwan da suka samo asali don yuwuwar aikace-aikacen warkewa a cikin cututtukan jijiyoyin jini, gami da cutar Alzheimer da rikicewar yanayi.

An binciko ƙarin haɓakar Uridine a matsayin dabarun tallafawa aikin fahimi da kuma rage alamun da ke tattare da cututtukan neurodegenerative.

Tushen Abinci: Ana samun Uridine ta dabi'a a cikin abinci daban-daban, gami da nama, kifi, kayan lambu, da kayan kiwo.