L-Tyrosine | 60-18-4

Tyrosine (wanda aka rage a matsayin Tyr ko Y) ko 4-hydroxyphenylalanine, ɗaya ne daga cikin amino acid guda 22 waɗanda sel ke amfani da su don haɗa sunadaran. Ya ƙunshi UAC da UAU. Amino acid ne mara mahimmanci tare da rukunin gefen iyaka. Kalmar "tyrosine" ta fito ne daga Girkanci tyros, ma'ana cuku, kamar yadda aka fara gano shi a cikin 1846 ta hanyar likitancin Jamus Justus von Liebig a cikin proteincasein daga cuku. Ana kiran shi tyrosyl lokacin da ake magana da shi azaman sashin layi na gefe na aiki.yrosine shine mafarin zuwa neurotransmitters kuma yana ƙara matakan plasmaneurotransmitter (musamman DOPAM da norepinephrine) amma yana da kadan idan wani tasiri akan yanayi. Tasiri a kan yanayi ya fi dacewa a cikin mutane da ke ƙarƙashin yanayin damuwa.
Baya ga kasancewar aminoacid proteinogenic, tyrosine yana da matsayi na musamman ta yanayin aikin phenol. Yana faruwa a cikin sunadaran da ke ɓangare na tafiyar da sigina. Yana aiki azaman mai karɓar ƙungiyoyin phosphate waɗanda ake canjawa wuri ta hanyar proteinkinases (wanda ake kira tyrosine kinases mai karɓa). Phosphorylation na ƙungiyar hydroxyl yana canza ayyukan furotin da aka yi niyya.
Har ila yau, ragowar tyrosine yana taka muhimmiyar rawa a cikin photosynthesis. A cikin chloroplasts (photosystem II), yana aiki azaman mai ba da gudummawar anelectron a cikin raguwar chlorophyll mai oxidized. A cikin wannan tsari, yana jure rashin lafiyar rukunin OH-phenolic. Daga baya an rage wannan tsattsauran ra'ayi a cikin photosystem II ta manyan gungu na manganese guda huɗu.
Yawancin bincike sun gano tyrosine tobe yana da amfani a lokacin yanayi na damuwa, sanyi, gajiya, asarar ƙaunataccen kamar mutuwa ko kisan aure, aiki mai tsawo da rashin barci, tare da raguwar matakan hormone na damuwa, raguwa a cikin damuwa da ke haifar da asarar nauyi da aka gani a ciki. gwaje-gwajen dabba, haɓakawa a cikin fahimi da aikin jiki da aka gani a cikin ɗan adam; duk da haka, saboda tyrosine hydroxylase shine ƙarancin ƙarancin enzyme, tasirin ba su da mahimmanci fiye da na L-DOPA.
Tyrosine ba ze da wani tasiri mai mahimmanci akan yanayi, fahimi ko aikin jiki a cikin yanayi na al'ada. Matsakaicin yau da kullun don gwajin asibiti da aka tallafawa a cikin wallafe-wallafen shine game da 100 mg / kg ga babba, wanda yakai kusan gram 6.8 a 150 lbs. Matsakaicin adadin ya kai 500-1500 MG kowace rana (kashi wanda yawancin masana'antun suka ba da shawarar; yawanci daidai da capsules 1-3 na tyrosine mai tsabta). Ba a ba da shawarar wuce 12000 MG (12 g) kowace rana.